![]() We are talking about a medium-sized institution of higher education, where about 10,000 people can complete a course each year. The cholesterol lowering effect was accompanied by reductions of malondialdehyde, oxyLDL receptor LOX-1 and phosphoPKB, which are all biomarkers of oxidative vascular damage, in peripheral polymorphonuclear cells.Īddition of BPF to rosuvastatin significantly enhanced rosuvastatin-induced effect on serum lipemic profile compared to rosuvastatin alone. ![]() This lipid-lowering effect was associated with significant reductions of biomarkers used for detecting oxidative vascular damage, suggesting a multi-action enhanced potential for BPF in patients on statin therapy.īergamot polyphenolic fraction Cardiometabolic risk Hyperlipidemia Rosuvastatin. All rights reserved.Chronic hepatitis B virus (HBV) infection is a major health problem worldwide. Although Italy is considered a low prevalence setting for HBV infection, following significant migration in recent years there has been an increase in the occurrence of the disease. Italian guidelines recommend that all migrants be screened, vaccinated and treated for HBV, as required. Unfortunately, screening and vaccination in this population can be challenging for several reasons. We therefore conducted an analysis to evaluate the efficacy and outcome of the pathways of care (from screening to treatment) for HBV in a population of migrants. Affiliations 1Associate Professor, Business Economics, Department of Clinical and Experimental Medicine, Magna Graecia University, Catanzaro, Italy. We evaluated 330 migrants who came to our centre between August 2015 and October 2018, and who were residing in seven different centres for refugees and asylum seekers. 3 Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health Università degli Studi di Genova Genoa Italy. 2Researcher, Business Economics, Department of Clinical and Experimental Medicine, Magna Graecia University, Catanzaro, Italy. 4 Science of Health Department Magna Graecia University Catanzaro Italy. 5 Department of Neuroscience Istituto di Ricerche Farmacologiche Mario Negri IRCCS Milan Italy. At the first evaluation, only 30% of them had already received screening for HBV. After our intervention, 23 (6.9%) were diagnosed as HBsAg carriers, whereas 204 (61.8%) were potentially eligible for vaccination. At a follow-up evaluation of the latter group, only 56.9% had by then been vaccinated, 17.6% had the vaccination course ongoing, and 17.1% had not started their vaccination course. Among those who were HBsAg positive, 73.9% were still in care at month 6 of follow-up, and only 43.3% were in care one year later. Our results demonstrated that both screening and vaccination strategies for HBV need to be improved in migrant populations. ![]() Affiliations 1 Department of Medical and Surgical Sciences, Infectious and Tropical Diseases Unit, 'Magna Graecia' University, Catanzaro, Italy. Similarly, a reinforcement of the network to keep in care migrants who initiated treatment or deserve clinical monitoring is necessary. 2 Department of Health Sciences, Clinical Microbiology Unit, 'Magna Graecia' University, Catanzaro, Italy.
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